Prenol lipids
![eMolecules 13293-47-5 | (+)-Isopinocampheylamine | Combi-Blocks, Inc. | MFCD00192239 | 153.269 | C10H19N | 95.000 | C[C@H]1[C@@H]2C[C@H](C[C@@H]1N)C2(C)C | 5g | 589788550](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502186072.JPG-250.jpg)
eMolecules 13293-47-5 | (+)-Isopinocampheylamine | Combi-Blocks, Inc. | MFCD00192239 | 153.269 | C10H19N | 95.000 | C[C@H]1[C@@H]2C[C@H](C[C@@H]1N)C2(C)C | 5g | 589788550
(+)-Isopinocampheylamine | Combi-Blocks, Inc. | 13293-47-5 | MFCD00192239 | 153.269 | C10H19N | 95.000 | C[C@H]1[C@@H]2C[C@H](C[C@@H]1N)C2(C)C | 5g | 589788550
Medchemexpress LLC Rel-PROTAC PARP1 degrader | 99.0% | 1145.09 | 25 MG
rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM.
- Relative configuration of ROTAC PARP1 degrader
- Based on MDM2 E3 ligand
- Induces significant PARP1 cleavage
- Induces programmed cell death
- Inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM at 10 μM (24 h)
- Purity: 98.99%
- Molecular weight: 1145.09
- Appearance: Solid
- Color: White to off-white
- Soluble in DMSO (110 mg/mL)
![Medchemexpress LLC 2H-Indazole-7-carboxamide, 2-[4-[1-[17-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-1-piperazinyl]-16-oxo-3,6,9,12-tetraoxa-15-azaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]phenyl]- rel- | 99.0% | 1145.09 |...](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436876-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2H-Indazole-7-carboxamide, 2-[4-[1-[17-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-1-piperazinyl]-16-oxo-3,6,9,12-tetraoxa-15-azaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]phenyl]- rel- | 99.0% | 1145.09 |...
rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM.
- Relative configuration of ROTAC PARP1 degrader
- Based on MDM2 E3 ligand
- Induces significant PARP1 cleavage
- Induces programmed cell death
- Appearance: solid
- Color: white to off-white
- Inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM at 10 μM at 24 h
Selleck Chemical LLC Alantolactone
Alantolactone a naturally occurring eudesmane-type sesquiterpene lactone (SL) could induce activin/SMAD3 signaling and disrupt Cripto-1/activin receptor type II A interaction
eMolecules 2247544-02-9 | Medchem Express | WS-383 | 5mg | 536984017 | HY-126075A | 498.45 | C18H21Cl2N9S2
Ambeed | Benzo[c][125]thiadiazole-4-carbaldehyde | 1g | 572997019 | A778855 | 5170-68-3 | MFCD02681902 | 164.180 | C7H4N2OS
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eMolecules Building Block Tool<|a>
Apexbio Technology LLC Catalpol 2415-24-9 20mg
Catalpol (2415-24-9) is a small-molecule modulator targeting adrenal cortical cells It is designed to stimulate steroidogenic pathways thereby promoting androgen hormone secretion Catalpol exerts its biological activity primarily through upregulation of steroid biosynthesis and inhibition of inflammatory mediators In in vitro experiments evaluating steroid hormone biosynthesis catalpol demonstrates an inhibitory activity profile against inflammatory mediators with an IC50 value ranging approximately from 10 to 50 M depending on assay conditions and cell models used Based on these pharmacological properties catalpol holds research potential in adrenal cortex function studies regulation of androgen synthesis pathways and investigations of anti-inflammatory mechanisms
Cayman Chemical B71CD80 LNg Isoform EXrac
Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD80 expressed in HEK293 cells • Amino acids: 35-242 • MW: 51.7 kDa
Cayman Chemical PentnoIc AcId-d9 500mg
An internal standard for the quantification of pentanoic acid by GC- or LC-MS
Apexbio Technology LLC Glycyrrhizic acid 1405-86-3 20mg
Glycyrrhizic acid (CAS 1405-86-3) is a triterpenoid saponin antagonist targeting high mobility group box 1 (HMGB1) and inhibitor of monoamine oxidase (MAO) as well as cytochrome P450 enzymes (CYP3A4 CYP2C9 CYP2C19) and 11 -hydroxysteroid dehydrogenase type 2 (11 -HSD2) It is designed to antagonize HMGB1-mediated pro-inflammatory responses and oxidative stress inhibit the enzymatic activity of MAO and 11 -HSD2 and modulate cytochrome P450-mediated metabolism Glycyrrhizic acid exerts its biological activity primarily through competitive inhibition of these enzymes It demonstrates MAO inhibition with an IC50 of approximately 0 16 M and competitively inhibits CYP3A4 (IC50 8 2 M) CYP2C9 ( 42 9 M) and CYP2C19 ( 40 3 M) Based on these pharmacological properties glycyrrhizic acid holds research potential in anti-inflammatory pathways enzyme inhibition and glucose metabolic modulation
Medchemexpress LLC Macimorelin acetate | 945212-59-9 | 99.3% | 534.61 | 25 MG
Macimorelin acetate is a GH secretagogue and an orally active GHSR agonist. It stimulates GH release and can be used in research for adult growth hormone deficiency (AGHD) and Cancer anorexia-cachexia syndrome (CACS).
- GH secretagogue
- Orally active GHSR agonist
- Stimulates GH release
- Applicable in research for adult growth hormone deficiency (AGHD)
- Applicable in research for Cancer anorexia-cachexia syndrome (CACS)
- High purity: 99.3%
Selleck Chemical LLC Trolox-100mg
Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.
Medchemexpress LLC L-Linalool 500mg | 126-91-0 | 154.25 g/mol | C10H18O | 500 MG
L-Linalool ((-)-linalool) is a naturally occurring monoterpene alcohol (C10H18O) with a molecular weight of 154.25 g/mol. It is supplied as a high-purity liquid analytical standard for laboratory research and analytical applications. L-Linalool has reported sedative and anxiolytic properties and has been used in neuropharmacology and Parkinson's disease studies. Not for human use.
- High purity analytical standard (~98%)
- Colorless to light yellow liquid, density 0.8657 g/cm³
- Used in neuropharmacology and Parkinson's disease research
- Suitable for analytical and research applications
- Available in small laboratory pack sizes (e.g., 500 mg)
Accela Chembio Inc MF: C33H49P | MW: 476.72 | ?97% | Flash Point: 317.7 celsius | BP: 569.8 celsius at 760 mmHg.
MF: C33H49P | MW: 476.72 | ?97% | Flash Point: 317.7 celsius | BP: 569.8 celsius at 760 mmHg.
